Get the F%$#ing Vaccine

No, I am not referring to the Covid vaccine, I am referring to the HPV vaccine. 

A historic new study out of Scotland shows the real-world impact of vaccines against the human papillomavirus: The country has detected no cases of cervical cancer in women born between 1988-1996 who were fully vaccinated against HPV between the ages of 12 and 13.

Many previous studies have shown that HPV vaccines are extremely effective in preventing cervical cancer. But the study, published on Monday in the Journal of the National Cancer Institute, is the first to monitor a national cohort of women over such a long time period and find no occurrence of cervical cancer.

(Emphasis mine)

………

The authors of the Scotland study monitored the records of all women born between 1988 and 1996 who were eligible for cancer screening, about 450,000 women. Of that group, 40,000 were vaccinated between the ages of 12 and 13, and 124,000 received the vaccines at or after 14 years of age. The remaining women, nearly 300,000, were not vaccinated.

No cases of cervical cancer were found among the women who were vaccinated before they turned 14, even if they had only received one or two doses of the vaccine rather than the full, three-dose protocol. Also noteworthy is that women who received the three-dose protocol between the ages of 14 and 22 also benefited significantly. While some cases of cervical cancer were recorded in this group, the incidence (3.2 cases per 100,000 women) was two and a half times lower than among unvaccinated women (8.4 cases per 100,000 women).

………

The types of vaccine administered to the cohorts monitored in the study changed as newer ones became available, covering more types of HPV. Until 2012, the vaccine in use was the bivalent Cervarix, targeting HPV 16 and 18. Then the quadrivalent Gardasil was administered until 2023, when the nonavalent Gardasil 9 was introduced.

This is why it’s still possible that cervical cancers may still arise even in vaccinated women, caused by the HPV strains not targeted by the earlier vaccines. “There are obviously other HPV types that cause cancer,” Palmer said, noting that the current results don’t mean cases of cervical cancers, caused by less high-risk strains of HPV, won’t emerge in the analyzed cohort in the future.

It should be noted that boys as well as girls should get the vaccine for two reasons, first, it mitigates the spread of HPV, and second, HPV associated penile cancer is rather common.

It is never too late to get the shot, but the sweet spot is 9-14 years old.